Anderson rested by England
England have rested James Anderson for the third and final Test against the West Indies, which starts at Edgbaston on Thursday.
Anderson's expected omission was confirmed on Sunday morning as he was rested ahead of a busy summer schedule.
He has been an almost ever-present in the past few years but will sit out the dead rubber against West Indies at Edgbaston as England look to protect the paceman from injury.
With bigger prizes looming on the horizon, none more so than the three-Test series against South Africa, England skipper Andrew Strauss had hinted immediately after the nine-wicket series-clinching win at Trent Bridge last week that the selectors would look to rotate their seamers.
England's number one Test status will go on the line against the Proteas and, with limited-overs series against West Indies and Australia to come before then, Anderson has been put in cotton wool.
New-ball partner Stuart Broad has been included in the squad announced this morning by the England and Wales Cricket Board, although the Twenty20 skipper could yet also be rested with quicks Steven Finn and Graham Onions retained in an otherwise unchanged 12-man squad.
Newly-capped Jonny Bairstow has therefore also kept his place in an unchanged batting list, meaning Ravi Bopara again misses out after a thigh injury initially ruled him out of the first two Tests.
Anderson has missed just one of England's past 25 Tests, since he was rested from the 2010 tour of Bangladesh, and national selector Geoff Miller said his omission had been in the "best interests" of the right-armer.
"James Anderson will miss this Investec Test as we look to manage his workload ahead of a busy period of cricket this summer and beyond, a decision which is in the best interests of the team and James himself," he said.
"We have been made to work hard for our two victories so far and are delighted to have secured the series, however we know that we will need to continue to play some good cricket if we want a third win against the West Indies this week."
Anderson has established himself as the leader of England's attack and admitted in the Mail on Sunday that he would be disappointed to be left out this week.
The 29-year-old revealed also that he was fully fit, despite showing signs of a slight quad injury during last week's Trent Bridge Test.
"It would be extremely disappointing for me to miss out," he said.
"It would be different if I felt fatigued or was struggling with an injury. But I believe I am fit to play - and while I am fit to play I want to play in every England game I can.
"Resting players is going to happen more and more often as the schedule gets busier and the ECB has been excellent at monitoring players to keep them fit and ready.
"Sure, this series has been hard work - back-to-back Tests always are; that's what we are used to and have to deal with the world over. But five days of rest is more than enough to be ready to play again."
Paceman Finn is the most likely replacement in the starting XI after he came in for an injured Anderson against Sri Lanka at Lord's last summer.
Onions would, however, be more of a like-for-like swap and he offered a timely reminder of his class by taking six wickets for Durham on Saturday as they almost snatched victory against county champions Lancashire at Chester-le-Street.
A recall for Onions would ensure his first Test appearance in two-and-a-half years after injuries have limited his international ambitions since.
England: Andrew Strauss (Middlesex, captain), Jonny Bairstow (Yorkshire), Ian Bell (Warwickshire), Tim Bresnan (Yorkshire), Stuart Broad (Nottinghamshire), Alastair Cook (Essex), Steven Finn (Middlesex), Graham Onions (Durham), Kevin Pietersen (Surrey), Matt Prior (Sussex, wicketkeeper), Graeme Swann (Nottinghamshire), Jonathan Trott (Warwickshire).