Arsenal v Man Utd preview
Arsene Wenger has a number of selection dilemmas, although he does have young striker Yaya Sanogo available again after five months out with a back injury following his summer switch from Auxerre.
Mathieu Flamini will be absent once again as he serves the final game of his suspension, while Aaron Ramsey (thigh), Kim Kallstrom (back) and Thomas Vermaelen (calf) remain side-lined through injury.
Theo Walcott and Abou Diaby are long-term absentees, but Wenger could make changes from the side that lost to Liverpool, with Tomas Rosicky, Lukas Podolski and Kieran Gibbs all vying for a return to the starting line-up.
Phil Jones and Marouane Fellaini will miss out once again for United as David Moyes looks to return to winning ways.
A calf injury kept Jones out of Sunday's 2-2 draw at home to Fulham, while Fellaini was also absent having failed to recover from a groin injury picked up last week.
Jonny Evans (calf) is also set to miss out, but Rio Ferdinand is once again included in the squad despite not featuring since last month's FA Cup defeat to Swansea.