Hicks stars in Twins win
Aaron Hicks delivered a walk-off RBI single with two outs in the bottom of the 10th inning to lift Minnesota to a 4-3 win over Boston.
Hicks' heroics came after Boston's All-Star closer Glen Perkins had blown a two-run lead in the ninth, and ensured the Twins took two of three games in the series against the defending champions.
Phil Hughes produced his fifth straight impressive start, giving up one run on five hits and striking out a season-high eight in six innings, while Chris Parmelee hit a two-run homer for the victors.
The New York Yankees edged the New York Mets 1-0 at Citi Field, Chase Whitley and Dellin Betances blanking the Mets.
Retiring Yankees shortstop Derek Jeter watched the last four outs of his final regular-season Subway Series game from the bench, having been pulled off the field in the bottom of the eighth inning.
Tyson Ross gave up three hits in seven innings as the San Diego Padres overcame Cincinnati 6-1 to ensure a split of Thursday's day-night double-header after the Reds had emerged 5-0 victors in the first game.
Rene Rivera hit an early two-run homer off Reds debutant Jeff Francis to give the Padres the upper hand in the second game, after Johnny Cueto had shut out the Padres for his third complete game in the opener.
Baltimore stayed top of the American League East with a 2-1 success against Kansas City. Nelson Cruz hit a home run in the fourth inning - his 12th of the year - as the Orioles halted a four-game losing streak, and handed the Royals a first defeat in four games.
Edwin Encarnacion connected twice and Juan Francisco added a solo shot to give the Toronto Blue Jays a 4-2 win over Cleveland, snapping the Indians' three-game winning streak.
Elsewhere, the Los Angeles Angels edged the Tampa Bay Rays 6-5, the Milwaukee Brewers rallied for a 4-3 win over the Pittsburgh Pirates, the St Louis Cardinals saw off the Chicago Cubs 5-3 and Michael Morse went deep and drove in three runs as the San Francisco Giants toppled the Miami Marlins 6-4.