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Hull KR will hand a debut to Travis Burns when they welcome Warrington to MS3 Craven Park on Sunday afternoon.
The Australian stand-off has been a frustrated spectator for the opening four rounds of the new Super League season due to a suspension carried over from his NRL career.
Burns' availability is timely, too, as Craig Hall - who has been playing in the half-backs alongside skipper Michael Dobson - is ruled out with an ankle injury.
Omari Caro is another absentee due to a shoulder problem, meaning Sandercock could hand a first start to former Batley Bulldog Alex Brown on the wing.
Lincoln Withers (toe) is also sidelined while Adam Walker is suspended after being handed a one-match ban for fighting in the closing minutes of last Sunday's 38-34 defeat to Salford.
George Griffin and Jordan Cox return to the 19-man squad after missing the disappointing reverse against the City Reds, the Robins having thrown away a 34-14 lead in the second half in front of the Sky Sports cameras.
Warrington welcome back Ben Westwood from suspension, the England international set to take the place of either Ben Currie or Tyrone McCarthy in the final line-up.
A stomach muscle tear rules out Joel Monaghan, so Wolves boss Tony Smith has recalled winger Rhys Williams from his loan spell at Salford as cover.
Chris Bridge, meanwhile, is due to make his return to action for Swinton against Dewsbury on the same day. The centre has yet to feature this year after having a knee operation in the off-season.
Hull KR: Salter, Brown, Ferguson, Horne, Griffin, Paterson, Mika, Tuimavave, Welham, Burns, J. Hodgson, Paea, Carlile, Cox, Dobson, D. Hodgson, Eden, Lovegrove, Latus.
Warrington: Atkins, Carvell, Cooper, Currie, Evans, Grix, Higham, Hill, Hodgson, Laithwaite, McCarthy, M. Monaghan, Myler, Ratchford, Riley, Waterhouse, Westwood, Williams, Wood.