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The Montreal Impact held on for a 2-1 victory in their all-Canadian MLS clash with Toronto FC to make it three wins out of three this season.
The Impact were two goals up at the break thanks to Patrice Bernier's penalty in the 34th minute and Marco Di Vaio's effort on the stroke of half-time.
Robbie Earnshaw pulled one back from the spot in the 68th minute, but Toronto could not find an equaliser.
The Philadelphia Union edged to a 1-0 win over the New England Revolution to stay three points behind Montreal in the Eastern Conference.
Jack McInerney grabbed the only goal of the game 14 minutes from time.
The rest of the day's games ended in draws.
Substitute Rodney Wallace netted in the last minute to earn a 1-1 draw for the Portland Timbers against the Sounders in Seattle.
Eddie Johnson scored for Seattle in the 13th minute.
The Columbus Crew were held to a 1-1 draw by the San Jose Earthquakes, who equalised through Justin Morrow (74) six minutes after Berti Glauber had given the home side the lead.
Alvaro Saborio salvaged a point for Real Salt Lake, scoring 10 minutes from time to cancel out the Colorado Rapids' opener, which came through Deshorn Brown (37), in another game which finished 1-1.
The other two games - New York Red Bulls v DC United and Sporting Kansas City v Chicago Fire - finished goalless.