Top seed Marin Cilic was ousted at the quarter-final stage by Japan's Kei Nishikori in Memphis on Friday.
The Croatian was outplayed as he was beaten 6-4 6-2 by Nishikori, the fifth seed, in the ATP Regions Morgan Keegan Championships.
Nishikori faces Australian Marinko Matosevic in the semi-finals after he defeated seventh seed Alexandr Dolgopolov in a hard-fought (6)6-7 6-2 6-4 result.
The other semi sees Feliciano Lopez meet Denis Istomin after both men beat American opponents.
Wild card Jack Sock could not match Lopez, a 6-4 6-3 winner, while Uzbek Istomin saw off Russell 6-4 7-6.
Update:
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