Plzen pleased, Anzhi seal win
Viktoria Plzen shocked Napoli 3-0 in the first leg of the Europa League last-32 tie, while Anzhi Makhachkala beat Hannover 3-1.
Plzen beat defending champions Atletico Madrid to top their group and are now heavy favourites to progress past the high-flying Italians after late goals from Stanislav Tecl and Frantisek Rajtoral built on Vladimar Darida's first-half opener.
Anzhi Makhachkala recovered from a goal down to defeat Hannover 3-1. Hannover took a 22nd-minute lead through Szabolcs Huszti but Samuel Eto'o drew Anzhi level soon after and Odil Ahmedov put the hosts ahead on 46.
Eto'o then spurned the chance to make it 3-1 in the 57th minute when his spot-kick was saved by Ron-Robert Zieler, but Anzhi were still able to secure a two-goal lead to take to Germany for the second leg thanks to Mbark Boussoufa.
Levante put aside their poor domestic form to claim an impressive 3-0 victory over 10-man Olympiacos. Goals from Pedro Rios, Jose Barkero and Obafemi Martins earned Juan Ignacio Martinez's men a notable scalp.
Goals by Toby Alderweireld and Ricardo Van Rhijn guided Ajax to a 2-0 victory over 10-man Steaua Bucharest at the Amsterdam ArenA.
Oscar Cardozo's second-half strike was enough to give Benfica a 1-0 victory at Bayer Leverkusen.
Two goals for Lazio from Libor Kozak as well as three penalties for Borussia Monchengladbach saw a breathless match end with the 10-man Italian club in pole position ahead of the second leg, with the tie poised at 3-3.
Atletico Madrid look to be heading out after they were beaten 2-0 at home by Rubin Kazan. Gokdeniz Karadeniz put the Russians ahead after six minutes before Pablo Orbaiz doubled their advantage in added on time.
Rodrigo Palacio scored twice following his early entrance as a substitute to put Inter Milan in control of their tie against Cluj. Palacio scored 10 minutes after that and added a late second in a 2-0 win.