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Sale go in search of their first Premiership success of the season against the Leicester Tigers on Friday night at the Salford City Stadium.
The league's bottom club show three changes from the side that suffered a fifth straight defeat of the season at Bath last weekend.
Wing Will Addison replaces Tom Brady, who is serving a two-week suspension, while Scotland international forwards Richie Gray and Richie Vernon both start. Fly-half Danny Cipriani is again on replacement bench duty.
Leicester welcome back scrum-half Ben Youngs, who makes his first appearance since suffering a shoulder injury on England's summer tour to South Africa.
George Ford partners Youngs at half-back instead of Toby Flood, who is on the bench, while centre Manu Tuilagi returns from injury and former London Irish flanker Richard Thorpe makes his Tigers debut.
Sale: 15 R Miller, 14 W Addison, 13 J Leota, 12 S Tuitupou, 11 M Cueto, 10 N Macleod, 9 C Willis, 1 E Lewis-Roberts, 2 T Taylor, 3 T Buckley, 4 R Gray, 5 F McKenzie, 6 R Vernon, 7 D Seymour (capt.), 8 A Powell. Replacements: 16 J Ward, 17 R Harrison, 18 V Cobilas, 19 K Myall, 20 J Gaskell, 21 N Fowles, 22 D Cipriani, 23 M Jennings.
Leicester: 15 N Morris, 14 A Thompstone, 13 M Tuilagi, 12 A Allen, 11 V Goneva, 10 G Ford, 9 B Youngs, 1 L Mulipola, 2 T Youngs, 3 M Castrogiovanni, 4 E Slater 5 G Kitchener, 6 J Crane (c), 7 R Thorpe, 8 T Waldrom.
Replacements: 16 G Chuter 17 B Stankovich, 18 D Cole, 19 R Andrew, 20 B Deacon, 21 S Harrison, 22 T Flood, 23 M Smith.