
Seeded trio Agnieszka Radwanska, Caroline Wozniacki and Marion Bartoli all crashed to second-round defeats in the Rome Masters on Wednesday.
Third seed Radwanska succumbed to a 6-4 4-6 6-1 loss to Czech Petra Cetkovska while former world number one Wozniacki, seeded sixth in Italy, was forced to retire due to illness after falling 6-4 4-0 behind to Anabel Medina Garrigues.
Wozniacki called for the trainer during the first set of her match in Rome, but she continued to struggle on before deciding she could not continue and it would appear she is now a doubt for the French Open which starts in less than two weeks' time.
Bartoli was out of sorts against Julia Goerges and the seventh seed fell to a crushing 6-3 6-1 defeat but there was but there was better news for eighth seed and reigning French Open champion Li Na, who dispatched Iveta Benesova 6-1 7-5.
Sam Stosur also made it through despite a spirited second-set fightback from home favourite Sara Errani, the fifth seed claiming a 6-3 7-5 victory.
Twelfth seed Angelique Kerber eased past Vania King 6-3 6-2, while Sorana Cirstea followed up her win over Jelena Jankovic with a comfortable 6-3 6-1 triumph over Sofia Arvidsson.
Elsewhere, Flavia Pennetta beat Sloane Stephens and Chanelle Scheepers defeated Marina Erakovic.
Update:
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