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Webb Simpson ceded the lead to DA Points as Lee Westwood and Ben Curtis set the clubhouse target at the Wells Fargo Championship.
Simpson, the overnight leader at 14 under par, dropped shots at the sixth and eighth holes of his final round having birdied the fifth at Quail Hollow.
That left Points, who had drawn level with a birdie at the second, at the top on his own at 14 under, one stroke ahead of Simpson and Rory McIlroy, who was one under for the day after an eventful front nine.
The Northern Ireland ace followed a birdie at the second with two successive bogeys, but back-to-back birdies at the seventh and eighth put him back in credit for the day.
Rickie Fowler joined the pair on 13 under with a birdie at the 10th, his fourth of the day, and Ryan Moore was in contention at 12 under, while Westwood and Curtis' 11-under total left them hoping for an unlikely series of slip-ups by the leading group.
A closing 66 - courtesy of an eagle at the seventh, five birdies and just a solitary dropped shot - meant the Englishman finished the week on a high, as did Curtis as he made five birdies in the last seven holes to finish with a 67.
Nick Watney was 11 under having played 10 holes, Australian John Senden was alone at 10 under after 12 and Westwood's compatriot Brian Davis was in a seven-strong group at nine under.