Wednesday begin at Brighton
Sheffield Wednesday start their Championship campaign away to Brighton & Hove Albion on 9 August.
Stuart Gray's Owls, who finished 16th last season, then face play-off runners-up Derby County in their opening home match a week later and Millwall, also at Hillsborough, in their third game.
Wednesday take on newly-promoted Rotherham at home on 8 November and the reverse fixture against their local rivals is on 21 March.
A home clash with Blackpool is scheduled for Boxing Day and there is another festive fixture away to Wigan Athletic on 28 December.
Sheffield Wednesday face fellow Yorkshire side Leeds United in their final home game and their season ends away to Watford on 2 May.
Opening three games:
August 9 - Brighton (a)August 23 - Derby (h)August 30 - Millwall (h)