Wigan end Saints' perfect record
St Helens saw their 100 per cent Super League record ended by a defeat to Wigan, while Huddersfield, Warrington and Castleford earned wins.
Reigning champions Wigan turned on the style to end the perfect start of neighbours St Helens in a Good Friday derby of pure quality in front of a sell-out Langtree Park crowd of 17,980.
England second-rower Liam Farrell produced two devastating finishes to score two of the Warriors' five tries and former St Helens scrum-half Matty Smith kicked six goals and a drop goal in a 33-14 victory, Wigan's fifth in a row that takes them to within four points of their table-topping rivals.
Wigan were also indebted to a wonderful all-round game from skipper Sean O'Loughlin, while second-rower John Bateman proved a revelation as a stop-gap centre.
Saints' tries came from in-form winger Tommy Makinson, who crossed twice to take his try tally to 11 in just nine games, and Jordan Turner.
Two tries from winger Rhys Evans and a 12-point haul from centre Chris Bridge helped Warrington to a convincing 44-6 derby success over Widnes at the Halliwell Jones stadium.
Evans claimed two second-half tries and Bridge scored a try and four goals from five attempts as Tony Smith's side bounced back to form after their somewhat indifferent start to the season.
The Wolves produced a superb first-half display to lead 24-0 at half-time through tries from Bridge, Michael Monaghan, Joel Monaghan and Gareth O'Brien, all converted by Bridge.
And they made sure of victory in the second half with Evans claiming his two tries and Ben Currie and Ryan Atkins also touching down with Stefan Ratchford adding two further conversions.
On a disappointing afternoon for the Vikings, Paddy Flynn claimed their only try six minutes from time which was a mere consolation effort which Danny Tickle converted.
Castleford shrugged off their heartbreaking setback to St Helens last time out by defeating local rivals Wakefield 43-20 at the Rapid Solicitors Stadium.
The Tigers blew a 24-6 lead against the Saints to lose 30-28 a week ago, but they returned to winning ways on Good Friday, with Richard Owen, Daryl Clark and Scott Wheeldon each scoring twice while there were also tries for Justin Carney and Liam Finn to consolidate third place in the First Utility Super League.
They were made to work for their win, though, and must have feared the worst when Wakefield scored two tries at the beginning of the second half to cut the deficit down to six points, but this time they held their nerve to hand the Wildcats their fifth successive defeat.
Winger Aaron Murphy scored a hat-trick of tries as Huddersfield halted their four-match losing run in emphatic fashion to put a dampener on Iestyn Harris' first home match in charge of Salford.
The 2013 league leaders dominated at the AJ Bell Stadium from start to finish, running in seven tries to five to secure a 42-22 victory in the First Utility Super League.
The only disappointment for the Giants was the loss of hooker Shaun Lunt with a knee injury 11 minutes from the end.