Top scorer Danny Hylton struck twice as Oxford came from behind to beat Northampton 3-1.
Team news for Tuesday's League Two clash between Northampton Town and Oxford United at Sixfields Stadium.
Boss Michael Appleton hailed Oxford's powers of recovery after they won their crucial basement battle with Tranmere.
A goal in each half brought Oxford a 2-0 win over Tranmere in the battle of the bottom two clubs in League Two.
Team news for Saturday's League Two clash between Oxford United and Tranmere Rovers at the Kassam Stadium.
Oxford have signed Charlton youngster Tareiq Holmes-Dennis on an initial one-month loan.
Two goals from Kwesi Appiah set the tone as Cambridge United came from behind to beat rivals Oxford United 5-1 in their Sky Bet League Two clash at the Abbey Stadium.
Cambridge United head coach Richard Money reacted with understandable delight after his side hammered Oxford United 5-1.