Clermont returned to the summit of the Top 14 standings in style on Saturday while Castres climbed out of the relegation zone thanks to a hard-fought win over Oyonnax.
The Scarlets bounced back from their hammering at the hands of Leinster with a seven-try, 43-0 thumping of hapless Treviso at Parc y Scarlets.
England fly-half hopeful George Ford inspired a Bath romp at the Recreation Ground as hapless Leicester were ruthlessly battered into submission.
Leicester boss Richard Cockerill admitted "we got what we deserved" after the Tigers suffered a humiliating 45-0 Aviva Premiership defeat against Bath at the Recreation Ground.
Harlequins director of rugby Conor O'Shea offered an impassioned defence of Chris Robshaw in reaction to a week of "insulting" speculation over his England future.
Harlequins rebounded from their surrender to Saracens by beating Wasps 26-23 in the Aviva Premiership, while Bath, Saracens and Sale also won.
London Irish director of rugby Brian Smith was proud of his side's performance despite seeing them deprived of a remarkable win over high-flying Saracens by a last-gasp Billy Vunipola try.
A last-minute try by Billy Vunipola from a driving maul saved Saracens' unbeaten record just as a rejuvenated London Irish had seemed set to pull off a remarkable Aviva Premiership victory.
Sale director of rugby Steve Diamond acknowledged there is plenty of room for improvement after his side secured their first win of the Aviva Premiership season at the expense of London Welsh.
Tom Arscott scored a hat-trick as Sale secured their first Aviva Premiership win of the season with a 46-8 thumping of London Welsh.
Glasgow Warriors aim to maintain their unbeaten start to the Guinness PRO12 season on Saturday as they travel to face Newport Gwent Dragons.
Saturday's Premiership action sees two London derbies, a battle of fly-halves, while London Welsh and Sale lock horns as both search for their first win of the season.